Week 6 of the 2018 college football season has so far been highlighted by a couple of major upsets.We had No. 7 Oklahoma losing to Texas and No. 5 LSU losing to Florida earlier this afternoon. Michigan State, ranked near the bottom of the top 25, also fell to Northwestern.Are any other upsets coming tonight?Mark May believes so.The former ESPN analyst is predicting a big one.May has Notre Dame falling on the road to Virginia Tech.“Mark it down, Notre Dame loses 31-30 today,” he writes.Mark it down, Notre Dame loses 31-30 today. @CoachLouHoltz88 @kevinctrimble @TheCrowdsLine— Mark May (@mark_may) October 6, 2018Will it happen?Notre Dame and Virginia Tech are set to kick off at 8 p.m. E.T. on ABC.